Dr Ford Brewer - PrevMed

Restoration of Vision Using Epigenetic Methods (by David Sinclair) - FORD BREWER MD MPH

Episode Summary

David Sinclair's team used a virus to insert Oct4, Sox2, and Klf4 (OSK) genes to reprogram youthful gene expression and DNA methylation. The study led to the restoration of sight in mice blinded at birth. The team also found this method to work for retinal blindness. The study shows that we're not losing our DNA or genes. But for some reason, when we age, we lose the ability to read them. Here's the link to the published article: https://www.biorxiv.org/content/10.1101/710210v1

Episode Notes

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