The ASPREE study was a trial of aspirin in 20,000 healthy adults, age 70 and older. It was published in September 2018 in the New England Journal of Medicine. Surprisingly, aspirin did not show a preventive benefit. Even more surprisingly, it showed an increased risk. And even more surprisingly, it was in cancer. Even the authors suggested that we look at these results with caution since there are meta-analyses that showed just the opposite. There's one more surprise. The mortality rate was less than half of that predicted in the study. This is being seen in several studies, such as the ASCEND trials. Are we getting healthier in our old age? Is this washing out benefits of less powerful interventions such as aspirin and low-dose Omega 3s?
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