Tumor growth rate or evolution of cancer is critical to the CRC screening process. It usually takes years for the development of an adenomatous polyp. And then from a polyp to an adenocarcinoma. That's important because it allows us time to continue screening over and over. If you do use the home screening methods, it takes years - and multiple samples to reliably pick up these samples. That's because these polyps are friable (meaning parts break off and bleed). But they don't bleed with every touch by feces. So, again, multiple samples are usually required - even if you're using DNA. What's the difference between FIT and FOBT ( fecal immunochemical testing vs fecal occult blood testing)? FOBT is looking at the heme molecule. It's a chemical test. There are a lot of cross-reactions that cause false positives. These range from red meats to even some plant components. The FIT test is an immunochemical test is an antibody test to human globin, the protein seat of the heme molecule. This makes a much better test and deals with false positives. Even upper gi bleeding doesn't cause a false positive. That's because upper gi blood is digested by the stomach and small intestine. Tumor growth rate or evolution of cancer is critical to the CRC screening process. It usually takes years for the development of an adenomatous polyp. And then from a polyp to an adenocarcinoma. That's important because it allows us time to continue screening over and over. If you do use the home screening methods, it takes years - and multiple samples to reliably pick up these samples. That's because these polyps are friable (meaning parts break off and bleed). But they don't bleed with every touch by feces. So, again, multiple samples are usually required - even if you're using DNA. What's the difference between FIT and FOBT ( fecal immunochemical testing vs fecal occult blood testing)? FOBT is looking at the heme molecule. It's a chemical test. There are a lot of cross-reactions that cause false positives. These range from red meats to even some plant components. The FIT test is an immunochemical test is an antibody test to human globin, the protein seat of the heme molecule. This makes a much better test and deals with false positives. Even upper gi bleeding doesn't cause a false positive. That's because upper gi blood is digested by the stomach and small intestine.
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